The United States Committee on Antimicrobial Susceptibility Testing

We help healthcare providers use the safest and most effective antibiotics to treat infected patients.

2025 USCAST STIC Tables Finalized

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We are pleased to announce that the 2025 USCAST in vitro susceptibility test interpretive criteria (STIC, also known as susceptibility breakpoints) tables are updated and finalized. USCAST wishes to thank all of those who attended our 2024 Virtual Meeting and provided comments on our proposed STIC. After considering all feedback, we have finalized for ceftriaxone and azithromycin against Neisseria gonorrhoeae, the oral cephalosporins, cephalexin, cefuroxime, and cefpodoxime, against E. coli and S. aureus, and trimethoprim-sulfamethoxazole against Enterobacterales for uncomplicated urinary tract infections. Updated STIC tables can be found here and video and slide presentations that support the USCAST STIC can be found here.

We Want to Hear From You! 

Is there a particular pathogen-drug combination you would like to see USCAST address? USCAST is committed to providing robust analyses to evaluate the STIC that clinicians and our community want. Please let us know by filling out this form.

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USCAST generates, integrates, and interprets data to support STIC for the benefit of patients. Through this website and our annual open public meeting, USCAST makes these data freely available to all interested parties.

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© United States Committee on Antimicrobial Susceptibility Testing 2023

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HOMEABOUTBREAKPOINTSDOCUMENTSPRESENTATIONS

USCAST generates, integrates, and interprets data to support susceptibility interpretative test criteria for the benefit of patients. Through this website and our annual open public meeting, USCAST makes these data freely available to all interested parties.

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